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Transgene Detail
Symbol: Tg(tetNZL)2Bjd
Name: transgene insertion 2, Hermann Bujard
MGI ID: MGI:3056772
Synonyms: Tg(tetNZL)2Uh
Transgene: Tg(tetNZL)2Bjd  Location: unknown  
Strain of Origin:  NMRI
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
Mutation detailsIn this transgene both the lacZ gene with a nuclear localization signal (NZ) and the luciferase gene (L) are driven by a bidirectional, tetracycline-responsive promoter element (TRE). (J:93001)
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Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
In conjunction with a second transgene expressing the tetracycline-controlled activator proteins tTA or rtTA coupled to a tissue-specific promoter (examples include: Tg(Camk2a-tTA)1Mmay, Tg(Myh6-tTA)6Smbf, and Tg(Nes-rtTA)306Rvs), transgenic mice express lacZ and luciferase in the appropiate tissue in a tetracycline-inducible fashion.
Original:  J:93001 Baron U, et al., Co-regulation of two gene activities by tetracycline via a bidirectional promoter. Nucleic Acids Res. 1995 Sep 11;23(17):3605-6
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.16
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