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Tg(GFAPGFP)14Mes
Transgene Detail
Nomenclature
Symbol: Tg(GFAPGFP)14Mes
Name: transgene insertion 14, Albee Messing
MGI ID: MGI:3056685
Synonyms: GFAP-GFP, GFAP::GFP, GFAPP-GFP, hGFAP::eGFP, hGFAP-GFP
Transgene: Tg(GFAPGFP)14Mes  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe transgene contains a mutant form of Green Fluorescent Protein (hGFP-S65T) under the control of the human astrocyte-specific glial fibrillary acidic protein (GFAP) promoter. (J:92998)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Notes
Bright fluorescence is observed in the cell bodies and processes of unfixed or fixed astrocyte preparations throughout the CNS of hemizygous mice. In addition retinal Mullers cells expressed the GFP transgene in response to degeneration of neighboring photoreceptors.
References
Original:  J:92998 Zhuo L, et al., Live astrocytes visualized by green fluorescent protein in transgenic mice. Dev Biol. 1997 Jul 1;187(1):36-42
All:  59 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory