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Crebbptm1.2Ltz
Targeted Allele Detail
Summary
Symbol: Crebbptm1.2Ltz
Name: CREB binding protein; targeted mutation 1.2, Beat Lutz
MGI ID: MGI:3056564
Synonyms: CBPfl
Gene: Crebbp  Location: Chr16:3899198-4031864 bp, - strand  Genetic Position: Chr16, 2.4 cM
Alliance: Crebbptm1.2Ltz page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:93192
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsFlp mediated recombination of the flanking frt sites results in the deletion of the neo cassette from Crebbptm1Ltz, leaving exon 2 flanked with loxP sites. (J:93192)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Crebbp Mutation:  99 strains or lines available
References
Original:  J:93192 Zhang Z, et al., Generation of a conditional allele of the CBP gene in mouse. Genesis. 2004 Oct;40(2):82
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory