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Foxf2W174R
Chemically induced Allele Detail
Nomenclature
Symbol: Foxf2W174R
Name: forkhead box F2; Trp174Arg
MGI ID: MGI:3056482
Synonyms: GSK 14H3
Gene: Foxf2  Location: Chr13:31625816-31631403 bp, + strand  Genetic Position: Chr13, 13.48 cM, cytoband A4
Foxf2W174R/Foxf2W174R pups are smaller at 3 days after birth and consume less milk at birth

Show the 5 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  (C3H/HeH x BALB/c)F1
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsENU mutagenesis induced a T to A transversion that results in the amino acid substitution of arginine for tryptophan at position 174 (W174R). (J:93069)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxf2 Mutation:  8 strains or lines available
Notes
Phenotypic Similarity to Human Syndrome: Anterior segment dysgenesis in homozygous mice (J:178103)
References
Original:  J:93069 Quwailid MM, et al., A gene-driven ENU-based approach to generating an allelic series in any gene. Mamm Genome. 2004 Aug;15(8):585-91
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/21/2017
MGI 6.07
The Jackson Laboratory