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Dll4tm1Grid
Targeted Allele Detail
Nomenclature
Symbol: Dll4tm1Grid
Name: delta-like 4 (Drosophila); targeted mutation 1, Tom Gridley
MGI ID: MGI:3056460
Gene: Dll4  Location: Chr2:119325784-119335962 bp, + strand  Genetic Position: Chr2, 59.97 cM, cytoband E3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:93125
Parent Cell Line:  GSI-1 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsPart of exon 1 and all of exons 2-6 were replaced with a PGK-neo cassette via homologous recombination. (J:93125)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dll4 Mutation:  15 strains or lines available
References
Original:  J:93125 Krebs LT, et al., Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants. Genes Dev. 2004 Oct 15;18(20):2469-73
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory