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Etv6tm2Sho
Targeted Allele Detail
Summary
Symbol: Etv6tm2Sho
Name: ets variant 6; targeted mutation 2, Stuart H Orkin
MGI ID: MGI:3056142
Synonyms: Floxed-neo+
Gene: Etv6  Location: Chr6:134012663-134247121 bp, + strand  Genetic Position: Chr6, 64.58 cM, cytoband G2
Alliance: Etv6tm2Sho page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:93052
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    LoxP sites were inserted to flank exon 7, which encodes the DNA binding domain. (J:93052)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Etv6 Mutation:  142 strains or lines available
References
Original:  J:93052 Hock H, et al., Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival. Genes Dev. 2004 Oct 1;18(19):2336-41
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory