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Tg(Tal1-cre/ERT)1Jrg
Transgene Detail
Nomenclature
Symbol: Tg(Tal1-cre/ERT)1Jrg
Name: transgene insertion 1, Joachim R Gothert
MGI ID: MGI:3055721
Synonyms: end-SCL-Cre-ERT, SCL-Cre-ERT
Transgene: Tg(Tal1-cre/ERT)1Jrg  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mutation detailsThe transgene is composed the 5' Tal1 enhancer element (from -7 to -0.9 kb relative to the transcription start site in exon 1a), the SV40 minimal promoter, and the Cre-ERT cassette, including a rabbit Beta-globin intron. The enhancer element drove endothelial-specific expression of the transgene. Cre was active in the presence of tamoxifen. (J:92965)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tal1     Summary of all recombinase alleles driven by Tal1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:92965 Gothert JR, et al., Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium. Blood. 2004 Sep 15;104(6):1769-77
All:  31 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory