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Cldn11tm1Sts
Targeted Allele Detail
Nomenclature
Symbol: Cldn11tm1Sts
Name: claudin 11; targeted mutation 1, Shoichiro Tsukita
MGI ID: MGI:3055494
Synonyms: Cld11-
Gene: Cldn11  Location: Chr3:31149920-31164324 bp, + strand  Genetic Position: Chr3, 15.14 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92955
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a neomycin resistance gene. RT-PCR of testes from mutant mice indicated no transcript was present. (J:92955)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cldn11 Mutation:  2 strains or lines available
References
Original:  J:92955 Kitajiri S, et al., Compartmentalization established by claudin-11-based tight junctions in stria vascularis is required for hearing through generation of endocochlear potential. J Cell Sci. 2004 Oct 1;117(Pt 21):5087-96
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory