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Stat5btm1Mam
Targeted Allele Detail
Nomenclature
Symbol: Stat5btm1Mam
Name: signal transducer and activator of transcription 5B; targeted mutation 1, Lothar Hennighausen
MGI ID: MGI:3055319
Synonyms: Stat5a/Stat5btm2Mam, Stat5fl
Gene: Stat5b  Location: Chr11:100780731-100850724 bp, - strand  Genetic Position: Chr11, 63.63 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92770
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation detailsTargeting vectors were designed to insert a floxed neo downstream of the gene. This allele was generated in conjunction with Stat5atm2Mam. (J:92770)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 10 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stat5b Mutation:  23 strains or lines available
References
Original:  J:92770 Cui Y, et al., Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation. Mol Cell Biol. 2004 Sep;24(18):8037-47
All:  77 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory