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Tg(PRG1)18Wlad
Transgene Detail
Nomenclature
Symbol: Tg(PRG1)18Wlad
Name: transgene insertion 18, Wyeth Lederle/Anne Deatly
MGI ID: MGI:3055287
Synonyms: PRG1, TGM-PRG-1
Transgene: Tg(PRG1)18Wlad  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6J x CBA/J)F1
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(PRG1)18Wlad expresses 1 gene
 
Mutation detailsThis line carries one copy of the human poliovirus receptor transgene (PVR). The human polio virus receptor is a member of the Igg superfamily. Northern and Western blot analyses of tissues from transgenic mice detected expression of the transgene at levels one third of levels detected in tissues from transgenic mice carrying ten copies of human PVR. (J:92990)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:92990 Deatly AM, et al., Characterization of mouse lines transgenic with the human poliovirus receptor gene. Microb Pathog. 1998 Jul;25(1):43-54
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory