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Foxp4tm1Eem
Targeted Allele Detail
Nomenclature
Symbol: Foxp4tm1Eem
Name: forkhead box P4; targeted mutation 1, Edward E Morrisey
MGI ID: MGI:3055161
Synonyms: Foxp4-
Gene: Foxp4  Location: Chr17:47867133-47924632 bp, - strand  Genetic Position: Chr17, 23.99 cM, cytoband C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92817
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace the majority of the forkhead domain (exons 12 and 13) with a neomycin resistance gene. Immunohistochemistry of mutant embryos confirmed lack of expression. (J:92817)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxp4 Mutation:  47 strains or lines available
References
Original:  J:92817 Li S, et al., Advanced cardiac morphogenesis does not require heart tube fusion. Science. 2004 Sep 10;305(5690):1619-22
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory