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Bhlhe23tm1Dbra
Targeted Allele Detail
Nomenclature
Symbol: Bhlhe23tm1Dbra
Name: basic helix-loop-helix family, member e23; targeted mutation 1, Debra E Bramblett
MGI ID: MGI:3054837
Synonyms: Bhlhb4-
Gene: Bhlhe23  Location: Chr2:180774381-180776900 bp, - strand  Genetic Position: Chr2, 103.34 cM, cytoband H3-H4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92623
Parent Cell Line:  AB2.1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace the entire gene with an IRES-LacZ/PGK-neo cassette. In situ hybridization indicated a lack of mRNA in mutant brain and retina. (J:92623)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bhlhe23 Mutation:  1 strain or line available
References
Original:  J:92623 Bramblett DE, et al., The transcription factor bhlhb4 is required for rod bipolar cell maturation. Neuron. 2004 Sep 16;43(6):779-93
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory