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Targeted Allele Detail
Symbol: Ahnaktm1Tak
Name: AHNAK nucleoprotein (desmoyokin); targeted mutation 1, Junji Takeda
MGI ID: MGI:3053964
Gene: Ahnak  Location: Chr19:8966648-9054278 bp, + strand  Genetic Position: Chr19, 6.04 cM, cytoband A
Germline Transmission:  Earliest citation of germline transmission: J:92500
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsHomologous recombination was used to delete approximately 3.2 kb of sequence including the ATG start codon. Western blot and immunoprecipitation of skin sections confirmed that no protein was expressed in mutant mice. (J:92500)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ahnak Mutation:  221 strains or lines available
Original:  J:92500 Kouno M, et al., Ahnak/Desmoyokin is dispensable for proliferation, differentiation, and maintenance of integrity in mouse epidermis. J Invest Dermatol. 2004 Oct;123(4):700-7
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.21
The Jackson Laboratory