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Targeted Allele Detail
Symbol: Npy1rtm1.1Wpg
Name: neuropeptide Y receptor Y1; targeted mutation 1.1, William P Gray
MGI ID: MGI:3053796
Synonyms: Y1-
Gene: Npy1r  Location: Chr8:66697192-66706792 bp, + strand  Genetic Position: Chr8, 33.15 cM, cytoband B3-C2
Germline Transmission:  Earliest citation of germline transmission: J:92582
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsCrossing Npy1rtm1Wpg mice with mice expressing Cre in the germ line excised the entire floxed region containing the coding sequence. Southern blot confirmed recombination. A radioligand binding assay indicated that mutant mice had negligible binding to the Npy1r specific antagonist. (J:92582)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Npy1r Mutation:  11 strains or lines available
Original:  J:92582 Howell OW, et al., Neuropeptide Y is neuroproliferative for post-natal hippocampal precursor cells. J Neurochem. 2003 Aug;86(3):646-59
All:  20 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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