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Tg(FABPCFTR)1Jaw
Transgene Detail
Nomenclature
Symbol: Tg(FABPCFTR)1Jaw
Name: transgene insertion 1, Jeffrey A Whitsett
MGI ID: MGI:3052981
Synonyms: FABP-hCFTR, Tg(FABPCFTR)#Jaw
Transgene: Tg(FABPCFTR)1Jaw  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(FABPCFTR)1Jaw expresses 1 gene
 
Mutation detailsThe transgene contains rat sequences for the fatty acid-binding protein (FABP) promoter and human sequence for the cystic fibrosis transmembrane conductance regulator homolog (CFTR) gene. Expression of the transgene was abundant in the ileum, jejunum, and duodenum and less abundant in the cecum and the colon. (J:21934)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:21934 Zhou L, et al., Correction of lethal intestinal defect in a mouse model of cystic fibrosis by human CFTR. Science. 1994 Dec 9;266(5191):1705-8
All:  43 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory