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Targeted Allele Detail
Symbol: Rph3altm1Sse
Name: rabphilin 3A-like (without C2 domains); targeted mutation 1, Susumu Seino
MGI ID: MGI:3051976
Synonyms: Noc2-
Gene: Rph3al  Location: Chr11:75830999-75938429 bp, - strand  Genetic Position: Chr11, 45.92 cM, cytoband B4
Germline Transmission:  Earliest citation of germline transmission: J:90669
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExon 3 was replaced with a neo in reverse orientation to transcription. Northern blot confirmed lack of transcript and Western blot showed no protein in mutant tissues. (J:90669)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rph3al Mutation:  13 strains or lines available
Original:  J:90669 Matsumoto M, et al., Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells. Proc Natl Acad Sci U S A. 2004 Jun 1;101(22):8313-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory