About   Help   FAQ
Socs3tm1Ayos
Targeted Allele Detail
Nomenclature
Symbol: Socs3tm1Ayos
Name: suppressor of cytokine signaling 3; targeted mutation 1, Akihiko Yoshimura
MGI ID: MGI:3051525
Synonyms: Socs3fl, Socs3flox
Gene: Socs3  Location: Chr11:117966079-117970047 bp, - strand  Genetic Position: Chr11, 82.96 cM, cytoband E2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92040
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Socs3 Mutation:  7 strains or lines available
References
Original:  J:92040 Yasukawa H, et al., IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages. Nat Immunol. 2003 Jun;4(6):551-6
All:  36 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/26/2014
MGI 5.19
The Jackson Laboratory