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Cyb5r4tm1Hfb
Targeted Allele Detail
Nomenclature
Symbol: Cyb5r4tm1Hfb
Name: cytochrome b5 reductase 4; targeted mutation 1, H Franklin Bunn
MGI ID: MGI:3050973
Synonyms: Ncb5or-
Gene: Cyb5r4  Location: Chr9:87022014-87077774 bp, + strand  Genetic Position: Chr9, 46.69 cM
Immunohistochemical and ultrastructural assessment of insulin- and glucagon-producing cells in Cyb5r4tm1Hfb/Cyb5r4tm1Hfb mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:91486
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cyb5r4 Mutation:  6 strains or lines available
References
Original:  J:91486 Xie J, et al., Absence of a reductase, NCB5OR, causes insulin-deficient diabetes. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10750-5
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory