About   Help   FAQ
Eno1Gt(ROSABetageo)1Ev
Gene trapped Allele Detail
Summary
Symbol: Eno1Gt(ROSABetageo)1Ev
Name: enolase 1, alpha non-neuron; gene trap 1, Martin Evans
MGI ID: MGI:3050549
Synonyms: GTE.2A4
Gene: Eno1  Location: Chr4:150321178-150333336 bp, + strand  Genetic Position: Chr4, 81.24 cM
Alliance: Eno1Gt(ROSABetageo)1Ev page
Mutation
origin
Mutant Cell Line:  GTE.2A4
Germline Transmission:  Earliest citation of germline transmission: J:48375
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: ROSABetageo     Vector Type: gene trap
 
Mutation detailsA gene trap vector inserted into the first intron of the gene. A fusion transcript containing the lacZ/neo genes from the inserted vector was expressed from this allele. Beta-galactosidase was detectable in embryonic mesoderm and adult testis. (J:48375)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Eno1 Mutation:  61 strains or lines available
Notes
ES cell line = CCE.1B
References
Original:  J:48375 Couldrey C, et al., Disruption of murine alpha-enolase by a retroviral gene trap results in early embryonic lethality. Dev Dyn. 1998 Jun;212(2):284-92
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory