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Csktm2Tara
Targeted Allele Detail
Nomenclature
Symbol: Csktm2Tara
Name: c-src tyrosine kinase; targeted mutation 2, Alexander Tarakhovsky
MGI ID: MGI:3050294
Synonyms: cskdelta
Gene: Csk  Location: Chr9:57626646-57653631 bp, - strand  Genetic Position: Chr9, 31.18 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:49654
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted in intron 8 and a floxed HSVtk-neo selection cassette was inserted in intron 10. The selection cassette and exons 9 and 10 were subsequently removed from properly targeted ES cells by transient cre expression. (J:49654)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Csk Mutation:  22 strains or lines available
References
Original:  J:49654 Schmedt C, et al., Csk controls antigen receptor-mediated development and selection of T-lineage cells. Nature. 1998 Aug 27;394(6696):901-4
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory