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Targeted Allele Detail
Symbol: Ntrk2tm1Jom
Name: neurotrophic tyrosine kinase, receptor, type 2; targeted mutation 1, James O McNamara
MGI ID: MGI:3050229
Synonyms: Trkbflox
Gene: Ntrk2  Location: Chr13:58806569-59133970 bp, + strand  Genetic Position: Chr13, 31.2 cM
Germline Transmission:  Earliest citation of germline transmission: J:91467
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsExon 1, which encodes the signal peptide and the first 40 amino acids of the N terminus, was flanked with 2 loxp sites. (J:91467)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ntrk2 Mutation:  44 strains or lines available
Original:  J:91467 He XP, et al., Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model. Neuron. 2004 Jul 8;43(1):31-42
All:  20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
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