Or8a1b^tm3Mom
Targeted Allele Detail

Summary

• Symbol: Or8a1b^tm3Mom
• Name: olfactory receptor family 8 subfamily A member 1B; targeted mutation 3, Peter Mombaerts
• MGI ID: MGI:3047232
• Synonyms: M72(FLAG)-IRES-tauGFP
• Gene: Or8a1b Location: Chr9:37622644-37623576 bp, - strand Genetic Position: Chr9, 20.8 cM
• Alliance: Or8a1b^tm3Mom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:91160
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Reporter)
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: Three residues were replaced in this mutant allele: E295D, V296Y, and L300D, within the predicted ORF. This converts EVKTALDK to a partial FLAG epitope, DYKTADDK, within the last cytoplasmic domain. An IRES-tauGFP was incorporated downstream of the coding sequence. (J:91160)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Or8a1b Mutation: 35 strains or lines available

References

• Original: J:91160 Feinstein P, et al., Axon guidance of mouse olfactory sensory neurons by odorant receptors and the beta2 adrenergic receptor. Cell. 2004 Jun 11;117(6):833-46
• All: 1 reference(s)