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Targeted Allele Detail
Symbol: Prkcdtm1Msg
Name: protein kinase C, delta; targeted mutation 1, Robert O Messing
MGI ID: MGI:3046799
Synonyms: PKC delta-, PKCdelta-
Gene: Prkcd  Location: Chr14:30595354-30626210 bp, - strand  Genetic Position: Chr14, 18.82 cM
Germline Transmission:  Earliest citation of germline transmission: J:91377
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsExon 2 was floxed and removed via transient cre-mediated recombination. Exon 2 contains the translation start codon. Northern blot showed absence of transcript in mutants and Western blot confirmed absence of protein in mutants. (J:91377)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Prkcd Mutation:  11 strains or lines available
Original:  J:91377 Chou WH, et al., Neutrophil protein kinase Cdelta as a mediator of stroke-reperfusion injury. J Clin Invest. 2004 Jul;114(1):49-56
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory