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Bub1btm1.1Jvd
Targeted Allele Detail
Nomenclature
Symbol: Bub1btm1.1Jvd
Name: budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae); targeted mutation 1.1, Jan M A van Deursen
MGI ID: MGI:3046581
Synonyms: Bub1b-
Gene: Bub1b  Location: Chr2:118598211-118641591 bp, + strand  Genetic Position: Chr2, 59.4 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:91128
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThis allele is derived from Bub1btm1Jvd via cre mediated recombination, which excises exon 5 and results in out-frame fusion of exons 4 and 6. (J:91128)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bub1b Mutation:  15 strains or lines available
References
Original:  J:91128 Baker DJ, et al., BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice. Nat Genet. 2004 Jul;36(7):744-9
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory