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Id3tm1Cmu
Targeted Allele Detail
Nomenclature
Symbol: Id3tm1Cmu
Name: inhibitor of DNA binding 3; targeted mutation 1, Cornelis Murre
MGI ID: MGI:3046425
Synonyms: Id3-
Gene: Id3  Location: Chr4:136143497-136145755 bp, + strand  Genetic Position: Chr4, 68.34 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:59969
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe sequences encoding the helix-loop-helix dimerization domain was replaced by a neo cassette via homologous recombination. Northern and western blot analysis confirmed the absence of transcript and protein, respectively, in homozygous mice. (J:59969)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Id3 Mutation:  8 strains or lines available
References
Original:  J:59969 Rivera RR, et al., Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3. Immunity. 2000 Jan;12(1):17-26
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory