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Syn2tm1Kao
Targeted Allele Detail
Nomenclature
Symbol: Syn2tm1Kao
Name: synapsin II; targeted mutation 1, Hung-Teh Kao
MGI ID: MGI:3045984
Gene: Syn2  Location: Chr6:115134902-115282626 bp, + strand  Genetic Position: Chr6, 53.2 cM, cytoband F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:91113
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon1 was replaced with a neomycin cassette inserted by homologous recombination. (J:91115)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Syn2 Mutation:  2 strains or lines available
Notes

Phenotypic Similarity to Human Syndrome: Epilepsy J:202031.

References
Original:  J:91113 Ferreira A, et al., Distinct roles of synapsin I and synapsin II during neuronal development. Mol Med. 1998 Jan;4(1):22-8
All:  28 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory