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Syn2tm1Pggd
Targeted Allele Detail
Nomenclature
Symbol: Syn2tm1Pggd
Name: synapsin II; targeted mutation 1, Paul Greengard
MGI ID: MGI:3045984
Synonyms: Syn2tm1Kao
Gene: Syn2  Location: Chr6:115111863-115258967 bp, + strand  Genetic Position: Chr6, 53.2 cM, cytoband F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:91113
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon1 was replaced with a neomycin cassette inserted by homologous recombination. (J:91115)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Syn2 Mutation:  16 strains or lines available
References
Original:  J:91113 Ferreira A, et al., Distinct roles of synapsin I and synapsin II during neuronal development. Mol Med. 1998 Jan;4(1):22-8
All:  38 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory