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Lect2tm1Ymg
Targeted Allele Detail
Summary
Symbol: Lect2tm1Ymg
Name: leukocyte cell-derived chemotaxin 2; targeted mutation 1, Satoshi Yamagoe
MGI ID: MGI:3045975
Synonyms: LECT2-
Gene: Lect2  Location: Chr13:56690277-56696315 bp, - strand  Genetic Position: Chr13, 30.08 cM
Alliance: Lect2tm1Ymg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:90961
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA pGK-neo cassette replaced all exons. Southern blot and PCR confirmed recombination and RT-PCR indicted lack of transcript in mutant livers. (J:90961)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lect2 Mutation:  12 strains or lines available
References
Original:  J:90961 Saito T, et al., Increase in hepatic NKT cells in leukocyte cell-derived chemotaxin 2-deficient mice contributes to severe concanavalin A-induced hepatitis. J Immunol. 2004 Jul 1;173(1):579-85
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory