About   Help   FAQ
Hip1rtm1Tsr
Targeted Allele Detail
Nomenclature
Symbol: Hip1rtm1Tsr
Name: huntingtin interacting protein 1 related; targeted mutation 1, Theodora S Ross
MGI ID: MGI:3045594
Synonyms: Hip1r-
Gene: Hip1r  Location: Chr5:123973628-124005558 bp, + strand  Genetic Position: Chr5, 63.3 cM, cytoband F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:89961
Parent Cell Line:  RW1 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2-8 were replaced with a neomycin resistance gene in the opposite orientation of the endogenous gene. Northern blot demonstrates absence of wild-type RNA in mutant brains and Western blot confirms absence of protein in mutant tissues. (J:89961)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hip1r Mutation:  27 strains or lines available
References
Original:  J:89961 Hyun TS, et al., Hip1-related mutant mice grow and develop normally but have accelerated spinal abnormalities and dwarfism in the absence of HIP1. Mol Cell Biol. 2004 Jun;24(10):4329-40
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/20/2017
MGI 6.10
The Jackson Laboratory