About   Help   FAQ
Hip1rtm1Tsr
Targeted Allele Detail
Nomenclature
Symbol: Hip1rtm1Tsr
Name: huntingtin interacting protein 1 related; targeted mutation 1, Theodora S Ross
MGI ID: MGI:3045594
Synonyms: Hip1r-
Gene: Hip1r  Location: Chr5:123973628-124005558 bp, + strand  Genetic Position: Chr5, 63.3 cM, cytoband F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:89961
Parent Cell Line:  RW1 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2-8 were replaced with a neomycin resistance gene in the opposite orientation of the endogenous gene. Northern blot demonstrates absence of wild-type RNA in mutant brains and Western blot confirms absence of protein in mutant tissues. (J:89961)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hip1r Mutation:  26 strains or lines available
References
Original:  J:89961 Hyun TS, et al., Hip1-related mutant mice grow and develop normally but have accelerated spinal abnormalities and dwarfism in the absence of HIP1. Mol Cell Biol. 2004 Jun;24(10):4329-40
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/20/2016
MGI 6.05
The Jackson Laboratory