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Targeted Allele Detail
Symbol: Ctnnbip1tm1Taki
Name: catenin beta interacting protein 1; targeted mutation 1, Tetsu Akiyama
MGI ID: MGI:3045424
Synonyms: ICAT-
Gene: Ctnnbip1  Location: Chr4:149518236-149566437 bp, + strand  Genetic Position: Chr4, 79.66 cM
Developmental defect images

Show the 2 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:90666
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsA neo cassette was inserted 11 amino acids downstream of the first initiation site via homologous recombination. Immunoblotting analysis confirmed the absence of protein expression in homozygous mice. (J:90666)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ctnnbip1 Mutation:  12 strains or lines available
Original:  J:90666 Satoh K, et al., Anteriorization of neural fate by inhibitor of beta-catenin and T cell factor (ICAT), a negative regulator of Wnt signaling. Proc Natl Acad Sci U S A. 2004 May 25;101(21):8017-21
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory