About   Help   FAQ
Recql4tm1Glu
Targeted Allele Detail
Summary
Symbol: Recql4tm1Glu
Name: RecQ protein-like 4; targeted mutation 1, Guangbin Luo
MGI ID: MGI:3045113
Synonyms: Recql4-
Gene: Recql4  Location: Chr15:76587753-76594748 bp, - strand  Genetic Position: Chr15, 36.28 cM, cytoband D3
Alliance: Recql4tm1Glu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:97101
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe targted mutation replaces a 1075bp genomic fragment encompassing part of exon 9 through exon 13 of the Recql4 gene with a PGKhprt-mini gene cassette. (J:97101)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Recql4 Mutation:  46 strains or lines available
References
Original:  J:97101 Mann MB, et al., Defective sister-chromatid cohesion, aneuploidy and cancer predisposition in a mouse model of type II Rothmund-Thomson syndrome. Hum Mol Genet. 2005 Mar 15;14(6):813-25
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory