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Recql4tm1Glu
Targeted Allele Detail
Nomenclature
Symbol: Recql4tm1Glu
Name: RecQ protein-like 4; targeted mutation 1, Guangbin Luo
MGI ID: MGI:3045113
Synonyms: Recql4-
Gene: Recql4  Location: Chr15:76703553-76710559 bp, - strand  Genetic Position: Chr15, 36.28 cM, cytoband D3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:97101
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe targted mutation replaces a 1075bp genomic fragment encompassing part of exon 9 through exon 13 of the Recql4 gene with a PGKhprt-mini gene cassette. (J:97101)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Recql4 Mutation:  24 strains or lines available
References
Original:  J:97101 Mann MB, et al., Defective sister-chromatid cohesion, aneuploidy and cancer predisposition in a mouse model of type II Rothmund-Thomson syndrome. Hum Mol Genet. 2005 Mar 15;14(6):813-25
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory