About   Help   FAQ
Nfe2l3tm1Vbl
Targeted Allele Detail
Nomenclature
Symbol: Nfe2l3tm1Vbl
Name: nuclear factor, erythroid derived 2, like 3; targeted mutation 1, Volker Blank
MGI ID: MGI:3045075
Synonyms: Nrf3-
Gene: Nfe2l3  Location: Chr6:51432670-51458768 bp, + strand  Genetic Position: Chr6, 24.84 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:89893
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsTwo exons were replaced with a floxed neomycin-cytosine deamidase cassette. Transcripts lacked CNC homology, DNA binding, and leucine zipper domains. (J:89893)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfe2l3 Mutation:  16 strains or lines available
References
Original:  J:89893 Derjuga A, et al., Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus. Mol Cell Biol. 2004 Apr;24(8):3286-94
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/15/2017
MGI 6.10
The Jackson Laboratory