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Targeted Allele Detail
Symbol: Nfe2l3tm1Vbl
Name: nuclear factor, erythroid derived 2, like 3; targeted mutation 1, Volker Blank
MGI ID: MGI:3045075
Synonyms: Nrf3-
Gene: Nfe2l3  Location: Chr6:51432670-51458768 bp, + strand  Genetic Position: Chr6, 24.84 cM
Germline Transmission:  Earliest citation of germline transmission: J:89893
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsTwo exons were replaced with a floxed neomycin-cytosine deamidase cassette. Transcripts lacked CNC homology, DNA binding, and leucine zipper domains. (J:89893)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfe2l3 Mutation:  18 strains or lines available
Original:  J:89893 Derjuga A, et al., Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus. Mol Cell Biol. 2004 Apr;24(8):3286-94
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory