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Targeted Allele Detail
Symbol: Tcf7l1tm1Efu
Name: transcription factor 7 like 1 (T cell specific, HMG box); targeted mutation 1, Elaine Fuchs
MGI ID: MGI:3044615
Synonyms: Tcf3LoxP
Gene: Tcf7l1  Location: Chr6:72626378-72789254 bp, - strand  Genetic Position: Chr6, 32.27 cM
Germline Transmission:  Earliest citation of germline transmission: J:90402
Parent Cell Line:  GS1 (ES Cell)
Strain of Origin:  129/Sv
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA 64 bp segment of exon 2 was flanked with loxP sites via homologous recombination. A loxP flanked neo cassette was removed via cre mediated recombination prior to generation of chimeric mice. (J:90402)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tcf7l1 Mutation:  71 strains or lines available
Original:  J:90402 Merrill BJ, et al., Tcf3: a transcriptional regulator of axis induction in the early embryo. Development. 2004 Jan;131(2):263-74
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory