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QTL Variant Detail
QTL variant: Brm2C3H/HeJ
Name: brachyury modifier 2; C3H/HeJ
MGI ID: MGI:3044387
QTL: Brm2  Location: Chr15:82641175-82641298 bp  Genetic Position: Chr15, cM position of peak correlated region/allele: 38.67 cM
QTL Note: genome coordinates based on the marker associated with the peak LOD score
Strain of Specimen:  C3H/HeJ
Allele Type:    QTL

Mapping and Phenotype information for this QTL, its variants and associated markers


Progeny with the most extreme tail length phenotype (T locus) that were derived again from the follwoing two crosses ((C3H females x B10-T males)F1 x B10 males and B10 females x (C3H females x B10-T males)F1 were analyzed for modifier loci effecting the expression of T. B10-T is a T mutation congenic. Quantitative trait analysis show a QTL locus, Brm2, significantly associated with a region of mouse Chromosome 15 including the D15Mit189 marker.

Original:  J:45873 Agulnik II, et al., Sex-specific modifiers of tail development in mice heterozygous for the brachyury (T) mutation. Mamm Genome. 1998 Feb;9(2):107-10
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
The Jackson Laboratory