About   Help   FAQ
Hsf1tm1Anak
Targeted Allele Detail
Nomenclature
Symbol: Hsf1tm1Anak
Name: heat shock factor 1; targeted mutation 1, Akira Nakai
MGI ID: MGI:3044161
Gene: Hsf1  Location: Chr15:76477445-76500972 bp, + strand  Genetic Position: Chr15, 35.95 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:90551
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2-4 were replaced with a neo cassette. Exons 2 and 3 encode the DNA-binding domain. Southern blot confirmed recombination. (J:89846)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hsf1 Mutation:  10 strains or lines available
References
Original:  J:90551 Inouye S, et al., Activation of heat shock genes is not necessary for protection by heat shock transcription factor 1 against cell death due to a single exposure to high temperatures. Mol Cell Biol. 2003 Aug;23(16):5882-95
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/05/2017
MGI 6.11
The Jackson Laboratory