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Sqstm1tm1Jmos
Targeted Allele Detail
Nomenclature
Symbol: Sqstm1tm1Jmos
Name: sequestosome 1; targeted mutation 1, Jorge Moscat
MGI ID: MGI:3043976
Synonyms: p62-
Gene: Sqstm1  Location: Chr11:50199366-50210827 bp, - strand  Genetic Position: Chr11, 30.36 cM, cytoband B1.2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:90010
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a neomycin selection cassette. Protein was undetected by Western blot analysis of homozygous mutant embryonic fibroblasts. (J:90010)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sqstm1 Mutation:  8 strains or lines available
References
Original:  J:90010 Duran A, et al., The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis. Dev Cell. 2004 Feb;6(2):303-9
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory