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Targeted Allele Detail
Symbol: Mlxipltm1Kuy
Name: MLX interacting protein-like; targeted mutation 1, Kosaku Uyeda
MGI ID: MGI:3043871
Synonyms: ChREBP-
Gene: Mlxipl  Location: Chr5:135089890-135138382 bp, + strand  Genetic Position: Chr5, 75.0 cM
Germline Transmission:  Earliest citation of germline transmission: J:89865
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe genomic region spanning exons 12 - 14 was replaced with a neo cassette via homologous recombination. Real-time RT-PCR confirmed the absence of mRNA expression in homozygous mice. (J:89865)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mlxipl Mutation:  29 strains or lines available
Original:  J:89865 Iizuka K, et al., Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis. Proc Natl Acad Sci U S A. 2004 Jun 11;101(19):7281-6
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory