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Atp8b1tm1Nbf
Targeted Allele Detail
Nomenclature
Symbol: Atp8b1tm1Nbf
Name: ATPase, class I, type 8B, member 1; targeted mutation 1, Nelson B Freimer
MGI ID: MGI:3043815
Synonyms: Atp8b1G308V
Gene: Atp8b1  Location: Chr18:64528979-64661000 bp, - strand  Genetic Position: Chr18, 37.49 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:89817
Parent Cell Line:  PC3 (ES Cell)
Strain of Origin:  129S4/SvJae-Tg(Prm-cre)70Og
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Atp8b1 Mutation:  4 strains or lines available
References
Original:  J:89817 Pawlikowska L, et al., A mouse genetic model for familial cholestasis caused by ATP8B1 mutations reveals perturbed bile salt homeostasis but no impairment in bile secretion. Hum Mol Genet. 2004 Apr 15;13(8):881-92
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory