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Doc2atm1Ytk
Targeted Allele Detail
Summary
Symbol: Doc2atm1Ytk
Name: double C2, alpha; targeted mutation 1, Yoshimi Takai
MGI ID: MGI:3042481
Synonyms: Doc2alpha-
Gene: Doc2a  Location: Chr7:126446588-126451877 bp, + strand  Genetic Position: Chr7, 69.25 cM, cytoband F4
Alliance: Doc2atm1Ytk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:89423
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe region spanning the start codon to exon 3 was replaced by LacZ and neo cassettes. Western blot confirmed lack of protein in mutants. (J:89423)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Doc2a Mutation:  14 strains or lines available
References
Original:  J:89423 Sakaguchi G, et al., Doc2alpha is an activity-dependent modulator of excitatory synaptic transmission. Eur J Neurosci. 1999 Dec;11(12):4262-8
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory