T^40H
Chemically induced Allele Detail

Summary

• Symbol: T^40H
• Name: brachyury, T-box transcription factor T; brachury 40 Harwell
• MGI ID: MGI:3042262
• Gene: T Location: Chr17:8653255-8661328 bp, + strand Genetic Position: Chr17, 4.92 cM
• Alliance: T^40H page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Nucleotide substitutions
• Mutation details: A missense mutation caused a substitution of valine for gluetamic acid substitution at position 64 in the first T-box domain. (J:93195)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any T Mutation: 60 strains or lines available

Notes

Mice homozygous for the 'satin' locus were mutagenised.

References

• Original: J:93195 Bogani D, et al., New semidominant mutations that affect mouse development. Genesis. 2004 Oct;40(2):109
• All: 1 reference(s)