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Ppargtm1.2Mtz
Targeted Allele Detail
Nomenclature
Symbol: Ppargtm1.2Mtz
Name: peroxisome proliferator activated receptor gamma; targeted mutation 1.2, Daniel Metzger
MGI ID: MGI:3041451
Synonyms: PPARgammaL2
Gene: Pparg  Location: Chr6:115361221-115490401 bp, + strand  Genetic Position: Chr6, 53.41 cM, cytoband E3-F1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:89238
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsCre-mediated recombination of Ppargtm1Mtz excised the floxed neo, leaving exons 1 and 2 floxed. PCR confirmed recombination. (J:89238)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pparg Mutation:  15 strains or lines available
References
Original:  J:89238 Imai T, et al., Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse. Proc Natl Acad Sci U S A. 2004 Apr 30;101(13):4543-7
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory