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Targeted Allele Detail
Symbol: Dnaja3tm1.1Jdl
Name: DnaJ heat shock protein family (Hsp40) member A3; targeted mutation 1.1, Jiing-Dwan Lee
MGI ID: MGI:3040717
Synonyms: Tid1f
Gene: Dnaja3  Location: Chr16:4639989-4707695 bp, + strand  Genetic Position: Chr16, 2.46 cM
Germline Transmission:  Earliest citation of germline transmission: J:89091
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsFlp-mediated recombination removed the frt-flanked neo cassette in Dnaja3tm1Jdl, leaving floxed exon 2. Western blot of mutant MEFs demonstrated protein expression was that of wild-type. (J:89091)
View phenotypes for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dnaja3 Mutation:  19 strains or lines available
Original:  J:89091 Lo JF, et al., Tid1, a cochaperone of the heat shock 70 protein and the mammalian counterpart of the Drosophila tumor suppressor l(2)tid, is critical for early embryonic development and cell survival. Mol Cell Biol. 2004 Mar;24(6):2226-36
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory