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Tg(rTH-Tag)20Dmc
Transgene Detail
Nomenclature
Symbol: Tg(rTH-Tag)20Dmc
Name: transgene insertion 20, Dona M Chikaraishi
MGI ID: MGI:3040267
Synonyms: TgN(rTH-Tag)20Dmc)
Transgene: Tg(rTH-Tag)20Dmc  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6NTac x DBA/2NTac)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThis transgene contains the rat tyrosine hydroxylase promoter and the wild-type allele of the SV40 large T antigen (Tag) gene. The construct also includes the rat tyrosine hydroxylase enhancer. (J:90323)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Transgenic mice on a genetic background involving C57BL/6Tac and DBA/2Tac display bone and brain stem tumors.
References
Original:  J:90323 Suri C, et al., Catecholaminergic cell lines from the brain and adrenal glands of tyrosine hydroxylase-SV40 T antigen transgenic mice. J Neurosci. 1993 Mar;13(3):1280-91
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory