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Mapk7tm1Jdl
Targeted Allele Detail
Nomenclature
Symbol: Mapk7tm1Jdl
Name: mitogen-activated protein kinase 7; targeted mutation 1, Jiing-Dwan Lee
MGI ID: MGI:3040180
Synonyms: BMKflox
Gene: Mapk7  Location: Chr11:61488812-61494406 bp, - strand  Genetic Position: Chr11, 37.96 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:89215
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExons 4-7 were flanked by loxP sites via homologous recombination. Transcript was detected in homozygous mutant livers. (J:89215)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mapk7 Mutation:  2 strains or lines available
References
Original:  J:89215 Hayashi M, et al., Targeted deletion of BMK1/ERK5 in adult mice perturbs vascular integrity and leads to endothelial failure. J Clin Invest. 2004 Apr;113(8):1138-48
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory