Tg(KRT14-Shh)#Mps
Transgene Detail

Summary

• Symbol: Tg(KRT14-Shh)#Mps
• Name: transgene insertion #, Matthew Scott
• MGI ID: MGI:3039792
• Synonyms: K14-Shh
• Transgene: Tg(KRT14-Shh)#Mps Location: unknown
• Alliance: Tg(KRT14-Shh)#Mps page

Transgene origin

• Strain of Origin: B6CBF2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT14-Shh)#Mps expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Shh (MGI:98297)

• The wild-type mouse sonic hedgehog homolog cDNA driven by a human keratin 14 (KRT14) promoter. (J:40166)

Tumor Data

List all tumor models in MMHCdb carrying Tg(KRT14-Shh)#Mps

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

In total, 26 transgenic mice derived from pronuclear injection were examined as embryos or neonates; lines could not be established because of perinatal lethality.

References

• Original: J:40166 Oro AE, et al., Basal cell carcinomas in mice overexpressing sonic hedgehog. Science. 1997 May 2;276(5313):817-21
• All: 1 reference(s)