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Idd17C57BL/6J
QTL Variant Detail
Nomenclature
QTL variant: Idd17C57BL/6J
Name: insulin dependent diabetes susceptibility 17; C57BL/6J
MGI ID: MGI:3038848
QTL: Idd17  Location: unknown  Genetic Position: Chr3, Syntenic
Variant
origin
Strain of Specimen:  C57BL/6J
Variant
description
Allele Type:    QTL
Mutation:    Undefined
    This allele confers resistance to insulin dependent diabetes compared to NOD. (J:42103)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Notes
Idd17 interacts with Idd10 to promote disease resistance.

Homozygosity for C57BL/6-derived alleles at both Idd10 and Idd17 confers significantly increased resistance to type 1 diabetes.

References
Original:  J:42103 Podolin PL, et al., Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two gene mediating the Idd10 effect and eliminates the candidate Fcgr1. J Immunol. 1997 AUG 15;159(4):1835-1843
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory