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Tlr9M1Btlr
Chemically induced Allele Detail
Nomenclature
Symbol: Tlr9M1Btlr
Name: toll-like receptor 9; mutation 1, Bruce Beutler
MGI ID: MGI:3038816
Synonyms: CpG1, Tlr9CpG1, unmethylated CpG-oligodeoxynucleotide unresponsive 1
Gene: Tlr9  Location: Chr9:106099797-106104075 bp, + strand  Genetic Position: Chr9, 57.46 cM
Mutation
origin
Strain of Origin:  C57BL/6
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsT to C transition at position 1496 results in a substitution of Leucine for Proline at amino acid 499. (J:88906)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tlr9 Mutation:  49 strains or lines available
References
Original:  J:88906 Tabeta K, et al., Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3516-21
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory