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Targeted Allele Detail
Symbol: Cd93tm1Mbo
Name: CD93 antigen; targeted mutation 1, Marina Botto
MGI ID: MGI:3038703
Synonyms: CD93-
Gene: Cd93  Location: Chr2:148436640-148443563 bp, - strand  Genetic Position: Chr2, 73.48 cM
Germline Transmission:  Earliest citation of germline transmission: J:88610
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin cassette replaced an 1128 bp fragment in exon 1. Absence of mRNA and protein expression was confirmed by RT-PCR and FACS analysis on peritoneal macrophages and immature B cells respectively. (J:88610)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd93 Mutation:  6 strains or lines available
Original:  J:88610 Norsworthy PJ, et al., Murine CD93 (C1qRp) contributes to the removal of apoptotic cells in vivo but is not required for C1q-mediated enhancement of phagocytosis. J Immunol. 2004 Mar 15;172(6):3406-14
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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