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Targeted Allele Detail
Symbol: Slc27a1tm1Jkk
Name: solute carrier family 27 (fatty acid transporter), member 1; targeted mutation 1, Jason Kim
MGI ID: MGI:3038701
Synonyms: Fatp1-, FATP1 KO
Gene: Slc27a1  Location: Chr8:71568882-71587302 bp, + strand  Genetic Position: Chr8, 34.43 cM, cytoband B3.3
Germline Transmission:  Earliest citation of germline transmission: J:88657
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe first exon was replaced with lacz by homologous recombination. Absence of Slc27a1 mRNA expression was confirmed with real time PCR. Microarray analysis indicated that there was no compensatory upregulation of other Slc27a in homozygotes (J:88657)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc27a1 Mutation:  20 strains or lines available
Original:  J:88657 Kim JK, et al., Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle. J Clin Invest. 2004 Mar;113(5):756-63
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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