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Tg(Actb-tTA)1Jzt
Transgene Detail
Nomenclature
Symbol: Tg(Actb-tTA)1Jzt
Name: transgene insertion 1, Joe Z Tsien
MGI ID: MGI:3038371
Synonyms: floxed-stop-tTA, stop-tTA
Transgene: Tg(Actb-tTA)1Jzt  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Transactivator)
Mutation:    Insertion
 
Mutation detailsThese transgenic mice express the tetracycline-inhibitable transcription factor (tTA) under the control of beta actin promoter. There is a floxed translational stop codon between the promoter and the tTA coding sequence. The tTA protein is only produced in cells where cre recombinase was expressed. (J:77659)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:77659 Shimizu E, et al., NMDA receptor-dependent synaptic reinforcement as a crucial process for memory consolidation. Science. 2000 Nov 10;290(5494):1170-4
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/17/2022
MGI 6.19
The Jackson Laboratory