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Tg(Cryaa-cre)10Mlr
Transgene Detail
Nomenclature
Symbol: Tg(Cryaa-cre)10Mlr
Name: transgene insertion 10, Mike Robinson
MGI ID: MGI:3038243
Synonyms: CPV14/Cre, cry-cre, Mlr10, MLR10-Cre
Transgene: Tg(Cryaa-cre)10Mlr  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThe expression of sequence encoding cre recombinase was driven by a modified alpha A crystallin promoter. The promoter consists of -282/+43 of the mouse Cryaa gene with an inserted copy of Pax6 consensus binding site in a 5' to 3' orientation at position -86 of the promoter. Seven lines were created with this line having expression of the transgene in both the lens epithelium and lens fiber cells but not in other parts of the eye. (J:88422, J:90292)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cryaa     Summary of all recombinase alleles driven by Cryaa.
 

Phenotypes
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Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:88422 Ebong S, et al., Characterization of the roles of STAT1 and STAT3 signal transduction pathways in mammalian lens development. Mol Vis. 2004 Feb 19;10:122-31
All:  22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory